The maximum proposed dose is a hundred mg and It is far from encouraged to consider more than one dose a day. Sildenafil could be taken with or without the need of food, but taking it which has a substantial-Excess fat meal may possibly increase the time before the medication starts Doing the job.
Even so, there aren't any managed scientific info on the safety or efficacy of VIAGRA in people with sickle cell or linked anemias.
Blood pressure level: Inform your doctor If you're getting medications to take care of high blood pressure. The combination of those medicines and sildenafil may perhaps increase on the hypertension-decreasing outcome of these medicines. It's also advisable to Allow your medical professional know In case you have or have had low hypertension.
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Pregnancy. It isn't acknowledged if or how sildenafil could influence pregnancy or damage an unborn little one. Tell your Health care supplier Should you be or system to be pregnant.
This metabolite has a PDE selectivity profile similar to sildenafil and an in vitro potency for PDE5 somewhere around fifty% in the parent drug. Plasma concentrations of this metabolite are close to 40% of These seen for sildenafil, so which the metabolite click here accounts for approximately 20% of sildenafil's pharmacologic effects.
Medical professionals ought to alert patients that prolonged erections better than four hrs and priapism (distressing erections better than 6 several hours in duration) have been documented occasionally since current market acceptance of VIAGRA.
Allergy symptoms to Components. People who find themselves allergic to any of the following mustn't take sildenafil.
At 24 hrs the plasma levels of sildenafil ended up still roughly 200 ng/mL, when compared to approximately 5 ng/mL when sildenafil was dosed alone. This really is in keeping with ritonavir's marked consequences with a broad variety of P450 substrates. VIAGRA had no impact on ritonavir pharmacokinetics [see DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS].
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Hearing: Situations of unexpected lessen or loss of hearing have already been reported postmarketing in temporal Affiliation with using PDE5 inhibitors, which include VIAGRA. In many of the circumstances, healthcare disorders and also other elements ended up reported which could have also performed a job inside the otologic adverse occasions.
Physicians really should advise clients from the possible for VIAGRA to enhance the hypertension lowering result of alpha-blockers and anti-hypertensive remedies. Concomitant administration of VIAGRA and an alpha-blocker could produce symptomatic hypotension in some clients.
You’ll choose Viagra by mouth about 1 hour in advance of sexual exercise. You ought to swallow the pill full.
Maintain sildenafil out of your get to of children. If you keep sildenafil oral liquid in a refrigerator, Make sure you preserve it away from little ones who also use the refrigerator.